Tentin tekstisisältö

ELT-63306 Modeling of Physiological Systems,

Exam 8.1.2014
1. Explain briefly: resu luuton
a) What are physiological homeostatic systems and N ?

b) How modeling of physiological systems (e.g. model of the heart) differs from modeling of
manmade objects (e.g. car engine)
c) Explain what are model, analog and analog model?

2. a) Compare Empirical model (black box model) versus theoretical model. How these
modeling methods work in modeling physiological systems?
b) Figure below left is measurement of lung volume as function of pressure: Describe how
you would use the data to build a black box model? Is it possible to build other kinds of
models using the data?

N TEN Emphysema
7
= 5 Normal
3 = s Sa
: z !
t

17

=

2 lf

33 Fibrosis

 

o 10 20 30 40
Tronseulmonary pressure (cm H20)

Flgure 34—7. Static expiratory pressure-volume curves of
lungs in normal subject and subjects with severe emphy-
sema and pulmonary fibrosis. (Modified, with permission,
from Pride NB, Mackem PT: Lung mechanics in disease.
Pages 659—692 of Vol III, Part 2, 01: Handbook of Physiol-
ogy. Seclion 3: The Respiratory System. Fishman AP [edi-
tor]. American Physiological Society, 1986.)

 

3. Inthe picture above right there is a FEM computational flow model of the blood pulse in
aorta (deformation+ pressure in grey scale). Describe a) how this kind of model can be
constructed (what data needed), and b) what kind of boundary conditions are reguired to
solve this model?

 

P.0. Box 692, 33101 Tampere, Finland, Tel.+358-3-3652116, Fax.+358-3-3652162
EMAIL: jari.hyttinen(&tut.fi.